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Please use this identifier to cite or link to this item: http://trail.tsuru.ac.jp/dspace/handle/trair/711

Title: 注意欠陥多動性障害(ADHD)および 破壊的行動障害における衝動性-その症状はドーパミン系、それともセロトニン系の制御不全のいずれによるのか-
Other Titles: Decomposing Impulsive Symptoms of ADHD and Disruptive Behavioral Disorders: Dopaminergic or Serotonergic Dysregulation?
Authors: 市原, 学
Other Authors: ICHIHARA, Manabu
Publisher: 都留文科大学
Language: ja
NCID: AN00149431
Journal Title: 都留文科大学研究紀要
刊行日付: 2015-10-20
Issue: 82
ISSN: 0286-3774
Start Page: 1
End Page: 9
Abstract: Attention-deficit hyperactivity disorder ( ADHD) is characterized by pervasive and impairing symptoms of inattention, hyperactivity, and impulsivity, being one of the most common neuropsychiatric disorders with childhood onset. Since the latter part of 1990’s, it has been hypothesized that ADHD symptoms are caused by neuropsychological dysfunction, namely executive dysfunction, specifically behavioral dysinhibition. Dopaminergic dysregulation in dorsolateral prefrontal cortex (DLPFC) is thought to be involved in these dysfunctions. But recent studies indicate ADHD symptoms may also occur from serotonergic dysregulation. In this case, oppositional defiant disorder (ODD) and conduct disorder (CD) are highly comorbid with ADHD, and SSRI can have more effect on the symptoms than metylphenidate hydrochlorine (MPH) or amphetamine. In the present review, the author looked into extant evidences with regard to “impulsivity” as multifaceted construct, and concluded that, while pure ADHD may be caused by behavioral dysinhibition ( impulsivity without emotional urgency), ADHD with ODD or CD may be caused by impulsivity with emotional urgency.
Type: Departmental Bulletin Paper
Textversion: publisher
URI: http://trail.tsuru.ac.jp/dspace/handle/trair/711
Keywords: ADHD
mpulsivity
behavioral inhibition
dopamine
serotonin
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